Locus Biosciences

cGMP Biomanufacturing Facility Upfit

As a pharmaceutical start-up, Locus needed a state-of-the-art environment to produce their products. Because their process involves virulent infective bacteria, the typical start-up approach of leasing space through a Contract Manufacturing Organization (CMO) quickly proved not to be an option. Locus needed to rapidly and efficiently design and build their own facility to produce a truly unique product. This upfit transformed a 30-year-old, one-story shell space into a cutting-edge BSL-2 laboratory and biomanufacturing space. This project provided for the build-out of 12,000 sf of additional space adjacent to the client’s existing suite to provide for clinical trial production, dispensing, and locker rooms. Additional scope included material air locks, personnel air locks, quarantine spaces, and support spaces. The project was built with maximum flexibility in mind to allow for process changes and potential future expansions. The small footprint unidirectional space flow paired with its industry-leading biopharma equipment provides a state-of-the-art facility to support a potential game-changing therapy with limitless disease fighting potential.

Thank you to your team for the excellent job in building out our new fully flexible and integrated BSL-2 GMP facility. The design and construction approach was executed by BE&K with the highest of quality and to Locus’ expectations. The construction program was an extension of our current and on-going operations, and the interaction between the two was seamless. Thank you again for a job well done.

— Paul Garofolo, President + CEO, Locus Biosciences

  • Service — Construction Management
  • Architect — Jacobs Engineering Group
  • Eagle Award Winner for Excellence in Construction — ABCC
  • Cell Therapy Manufacturing